Lexie: Yes, the odds are against us. I'm a one woman wrecking ball, all I do is break you. Your hand, your penis, your relationships, your life. I'd say our survival rate is about 3 percent. And that's, that's, that's bad. But, it's not nothing. And I don't think we should give up on this. At least not yet because...
Mark: (puts finger to Lexie's lips)
Lexie: Okay.
Mark: You think you broke me little Grey? You're the one that put me back together.

Mark: Have you heard of a... Doctor Nelson in Neuro?
Callie: Oh yeah. Haha, shadow Shepherd.
Mark: Shadow Shepherd?
Callie: Yeah, he's a solid surgeon, but sort of the JV player to Shepherd's Varsity. The B team to Shepherd's A. The brick layer to Shepherd's architect.
Mark: I get it! Just 'cause a guy doesn't publish fancy clinical trials, or takes on flashy surgeries, or has creepy perfect hair, he's less of a man?
Callie: Kinda.

Callie: You realize that as your doctor I'm not recommending this right?
Mark: I need to get through my surgeries today.
Callie: Oh you're gonna get through them. You're just gonna be in a world of hurt later.

Lexie: HI!
Mark: HAND!
Lexie: Hand! Oh god! I'm sorry! I forgot. I'm so sorry. I feel terrible, about everything. About the fight, and your hand, and Derek. You know he's not doing so well, I really think that you should talk to him.
Mark: I should talk to him?
Lexie: Mhmm.

Mark: What are you doing?
Callie: I went all... say anything on the peades surgeon, in front of the peds surgeons date. So now I am hiding from the peades surgeon.
Mark: Hm, mature.
Callie: Um, you got in a fist fight. No judging!

Callie: It's still swollen. I'd give it another day of rest.
Mark: I haven't operated in 3 days!
Callie: Don't hit people with your scalpel hand. Have you talked to him yet?
Mark: He threw the first punch.
Callie: You did catch him at a bad time.
Mark: So he lost a patient. Boo hoo! We're surgeons. We're men. We lose patients. It doesn't give him the right to go around behaving like a drunk frat boy. Now I'm supposed to go crawling back begging for his forgiveness?

Mark: Dr. Grey. It would appear that congratulations are in order.
Lexie: Thank you, Dr. Sloan.
Mark: And I'd also like it acknowledged that I offer these congratulations, professionally and respectfully, without any innuendo or inappropriate body language.
Lexie: Acknowledged, Dr. Sloan.

Callie: You're an idiot. What is your problem?
Mark: He is proposing to her. That makes Little Her, his little sister. And I can't sleep with any more sisters. And she's young. And I'm her boss.
Callie: And I'm celibate.

Mark: Well, you're all set here, I'll leave you to it.
Derek: Thanks.
Mark: Congratulations.
Derek: Thanks.
[phone rings]
Derek: Addison? ... What happened?

Derek: This is stupid. She's gonna hate this.
Mark: What? Flowers? Girls love this crap.
Derek: It's cliche. I'm a cliche!
Mark: Cliches became cliches for a reason. Because they worked. It's great isn't it. When you feel so strongly for someone and it's not just about the sex, it is... it's true.
Derek: Ha, ha, ha... you should not talk like that.

Richard: It's the opening page of your marriage. It can determine the entire game. You've gotta go all out. Now your plan should include: Flowers, candles, exotic foods, live musicians, and a row boat. Sky writing is not out of the question. You've gotta go...
Meredith: Dr. Shepherd.
Derek: Yes?
Richard: Ah, you've gotta... um... hmm... yeah.

Mark: [sees Mer walk by, clears throat] So what did you use, like, a twist drill for that?
Derek: Oh no, you don't want a partial propriatal heamatoma! [laughs]
Meredith: Hi.... [walks away]
Owen: Good luck.
Derek: Ahhh... Please don't tell anybody else ok? I thought I could trust you.
Mark: Of course you can trust me.

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey