(The Professor is poking a comatose Leela with his poking stick)
Fry: Poke harder damnit!
Farnsworth: I'm poking as hard as I can!

Bender: So where are we going?
Professor: Pandora.
Leela: That dangerous 3D planet? Can't we just send our avatars?
Professor: No, it's cheaper just to have you die.

Guenter: All I want out of life is to be a monkey of moderate intelligence who wears a suit. That's why I've decided to transfer to business school!
Farnsworth: Nooo!

Professor: I sent Beder to get a copy of The Last Supper.
Bender: Everyone at Kinkos was an idiot so I just stole the original.
Zoidberg: Jesus Christ! aAd there's twelve apostles!

Ah, to be young again. And also a robot.

Prof. Farnsworth: Good news everyone!
Bender: I don't like the sound of this.
Prof. Farnsworth: You're all off to Trisol, a planet with three suns-
Bender: Here it comes-
Prof. Farnsworth: Deep in the heart of the Forbidden Zone!
Bender: Thank you and goodnight.

Leela: You're Fry's relative. Do you have any idea how he got so crazy?
Prof. Farnsworth: Uh, what? Oh, yeah, they say madness runs in our family. Some even call me mad. And why? Because I dared to dream of my own race of atomic monsters, atomic supermen with octagonal shaped bodies that suck blood...

Come on stem cells, work you astounding scientific nonsense.

You can't simply know something by assembling a committee of words! That's it! I'll assemble your comittee!

Professor: Then we plunged into a massive worm hole, never to be seen again...
Bender: Yeah we're back!
Hermes: Sweet coincidence of Port Au Prince, we're back at Earth!
Professor: Of course! That was the Panama worm hole, Earth's central channel for shipping.
Dr. Zoidberg: How humorous.
Professor: It's sort of a Comedy Central shipping channel and now we're on it.
Amy: I get it!

Fry: I don't get this. Is Blernsball exactly the same as baseball?
Farnsworth: Baseball? God forbid.
Leela: Face it, Fry, baseball was as boring as mom and apple pie. That's why they jazzed it up.
Fry: Boring? Baseball wasn't... hmm, so they finally jazzed it up?

He's good, alright. But he's no Clem Johnson. And Johnson played back in the days before steroid injections were mandatory.

Futurama Quotes

Dear Captain's Diary; I may not have found love on this mission but I did find a cute little companion who excretes starship fuel. And that's just as good.

Leela

Amy: Is it possible to get everyone back to normal using four or more bodies?
Professor: I'm not sure. I'm afraid we need to use... math!