Leela: Depth at 45 hundred feet, 48 hundred, 50 hundred! 5000 feet!
Farnsworth: Dear Lord, that's over 150 atmospheres of pressure.
Fry: How many atmospheres can this ship withstand?
Farnsworth: Well it's a spaceship, so I'd say anywhere between zero and one.

Professor: I sent Beder to get a copy of The Last Supper.
Bender: Everyone at Kinkos was an idiot so I just stole the original.
Zoidberg: Jesus Christ! aAd there's twelve apostles!

Farnsworth: We, by which I mean you, will have to rush him to his ancient homeworld, which will shortly erupt in an orgy of invertebrate sex.
Fry: Oh, baby. I'm there!
Leela: Fry, do you even understand the word invertebrate?
Fry: Nope, but that's not the word I'm interested in. No need to pack pants, people. Let's roll!

Fry: I don't get this. Is Blernsball exactly the same as baseball?
Farnsworth: Baseball? God forbid.
Leela: Face it, Fry, baseball was as boring as mom and apple pie. That's why they jazzed it up.
Fry: Boring? Baseball wasn't... hmm, so they finally jazzed it up?

Come on stem cells, work you astounding scientific nonsense.

He's good, alright. But he's no Clem Johnson. And Johnson played back in the days before steroid injections were mandatory.

Professor: Dr. Zoidberg, can you note the time and declare the patient officially dead?
Dr. Zoidberg: Can I? That's my speciality!

Amy: Then take some Echinacea or a St. John's wort.
Farnsworth: Or a big fat placebo. It's all the same crap.

Farnsworth: Who are those horrible orange creatures over there?
Glermo: Why those are the Grunka-lunkas; they work here in the Slurm factory.
Farnsworth: Tell them I hate them.

Fry: Now just read these cue cards... And action!
Farnsworth: Miss McNeal, I'm afraid I must decline your offer of marriage. For, you see, I'm dying. Cough, then fall over dead.
Zoidberg: My God, he's dead.
Farnsworth checks his pulse

Farnsworth: I need it shipped to my office at Mars University. It's a little experiment that may well win me the Nobel Prize.
Leela: In what field?
Farnsworth: I don't care, they all pay the same.

Farnsworth: So what are you doing to protect my constitutional right to bear doomsday devices?
N.R.A. Man: Well, first off, we're gonna get rid of that three-day waiting period for mad scientists.
Farnsworth: Damn straight! Today, the mad scientist can't get a doomsday device, tomorrow it's the mad grad student. Where will it end?
N.R.A. Man: Amen, brother. I don't go anywhere without my mutated anthrax... for duck hunting.

Futurama Quotes

(after he freezes Leela)
Fry: See ya' in a thousand years.
(Is about to leave, then comes back and switches it from 1000 years, to five minutes)
Fry: You owe me.

Leela: Look, I know it's not much consolation. But, I understand how you feel.
Fry: No, you don't. I've got no home, no family.
Bender: No friends.
Fry: My whole world is gone. You can't possible understand what it feels like to be so alone.
Leela: I understand. I'm the only one-eyed alien on this whole planet. My parents abandoned me here as a baby and I don't even know what galaxy they were from. I know how it feels to be alone.