Serena: So you're going to let Chuck have the assistant position then.
Blair: I said civilized, not lobotomized.

A good scandal is one thing, but even Gossip Girl likes to keep things classy and somewhat true.

Serena: I mean who would lie to Gossip Girl about something like that?
Blair: Do you really want a list? Because I don't know if I have that kind of time.

Serena: The problem is I've been late for my English Lit class a few times and lates count as absences, which —
Blair: If only there were a device of some kind to keep the time.

Serena: With Dan and Nate behind me I really feel like I can bury the old me and start anew.
Blair: May you rest in peace.

Serena: B, can I talk to you for a minute?
Blair: Yes. [to Minion #1] Five paces behind. For privacy. [to Minion #2] Ten for you.

Serena: It was just so easy in Paris.
Blair: You were just so easy in Paris.

Serena: I guess it's for the best. If I end up with Dan, a part of me will always love Nate. If I end up with Nate, a part of me will always love Dan, so I don't know. I guess I just need to find someone who gives me what I get from both of them.
Blair: That's a mature decision. Not sure I've made many of my own for awhile.

Serena: [to Dan] I'll call you later.
Blair: No she won't!

Serena: Even though you may regret entering my world, at least you've developed terrific social espionage skills.
Dan: Well as they say, adapt or die.

Fine. You know what? I will stay away from Nate and Dan. But you have to stay away from Chuck and Eva. No plotting. No meddling. No Blair Waldorfing.

Serena: Did you just get a key?
Girl: Yep. And my mom said I'd never get in unless I lost 10 pounds. She's a bitch.

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.