I think this is the Olympics of self-pity.

Watson

I'm telling you right now that you did not kill that woman.

Watson

I don't understand the questions. Could I have more information?

Bella

Maybe because Wyatt Earp got back into his time machine and disappeared.

Watson

What's up with the nerd brigade?

Joan

This woman wasn't just murdered. She was rapidly turning into a mummy.

Sherlock

What do you say, Watson? Will you help?

Kitty

Joan: That's the sex blanket.
Sherlock: I've asked you not to call it that.

Harlan: You were my friend.
Sherlock: I was your employer, Harlan. And you were my consultant. One of many.
Harlan: I know that I am a little obsessed with what I do. That has always made it hard to make friends. And I used to feel pretty bad about that and then I meet you. And I thought to myself, hey, if it doesn't bother him, why should I let it bother me? I got a lot out of the work we did. A lot. But if someone like you, thinks I'm a loser, then ...

I sort of travel in different mathematical circles...

Harlan

In the wrong hands, math can be manipulated, abused. I decided to do something about it. You catch people who murder other people. I catch people who murder math.

Harlan

Sherlock: Your home, Watson, is utterly pleasant.
Joan: You say that like it's a bad thing.
Sherlock: When you told me you wanted a life of your own, I didn't realize you meant you wanted the same life everyone else has ... anyway, it's none of my business.

Elementary Quotes

Holmes: Why do you suppose you hate your job so much?
Watson: I don't hate my job.
Holmes: You have two alarm clocks. No one with two alarm clocks loves their job. Two alarm clocks mean it's a chore for you to get up in the morning.

Watson: How do you do it, guess things?
Sherlock: I observe and then I deduce.
Watson: How did you know I was a doctor, you said you could tell from my hands.
Sherlock: Hand, singular. It was soft no calluses.
Watson: How did you know my father had an affair?
Sherlock: Google. Not everything is deducible.