Robbie: Game recognizes game.
Fiona: We are nothing alike.

Mandy: Random destruction makes you think of me?
Lip: Yeah it was beautiful.

What kind of system do we live in where you have to cripple yourself to stay alive?

Frank

Sasha needs to find out that my wife's a hooker, not a slave.

Mickey

You know I used to be your sister, not just an ATM.

Fiona

You let some dude finger you last night on the L?

V [to Fiona]

We’re all addicts Fiona, trying to fill a void. Some of us are just better at hiding it, right?

Robbie

Carl: What happened to the ghetto nurse?
V: She became a capitalist.

Get hard drugs, make daddy proud.

Frank [to Carl]

Frank: Wow so that’s my daughter, she’s kind of beautiful.
Carl: She looks like you in skank form.
Frank: Thank you son.

Sheila: Now what?
Debbie: Ask him if he’s DTF.
Sheila: DTF. What does that even mean?

Just when I think I’ve peeled the onion on Frank, bam another layer.

Fiona

Shameless Quotes

Everytime she pees on the stick it's bad news and then I get depressed thinking about my husband banging my mom cause we selfishly wanna have a baby with some of our DNA.

V

Gus: See you at two.
Fiona: Wouldn't miss it.