No, seriously, Sam, what are we gonna say? "Hi, my name is Sam Winchester, and this is my much handsomer brother, Dean. We hunt monsters, oh and that guy you were banging, we’re pretty sure he made a deal with a demon, so a hellhound came and dragged his soul to Hell. But you, you’re cool. And since there’s nothing around for us to kill, peace out."

Dean

Computers - monsters, porn, is there anything they can’t do?

Dean

Mary: I'm not just a mom, and you are not a child.
Dean: I never was.

It's not your job to make my lunch. Tuck me into bed at night. You make your own choices, even if I don't like 'em.

Dean

You’re changing the world, and I want to be a part of it.

Sam

Oh my dad. I love that. You and I, both single fathers. I could use a little dad advice right about now. When do you let ‘em date?

Lucifer

No one is born good or bad. It’s all in the upbringing.

Dagon

Nothing comes before my family, not even me.

Mary

You idiots. You’re all going to die.

Crowley

The things we’ve shared together, they have changed me. You’re my family. I love you. I love all of you.

Castiel

Dean: Dean: Like you said, we’re family. And we don’t leave family behind.

We kinda sound like heroes to me.

Dean

Supernatural Quotes

This is my voicemail, make your voice … a mail.

Castiel

You betrayed me? No one in the history of torture's been tortured with torture like the torture you'll be tortured with.

Crowley