He who hesitates, disintegrates.

Lucifer

Apparently archangel plus God power doesn’t trump God’s sister.

Sam

This is exactly how we screw ourselves. We make the heart choice instead of the smart choice.

Sam

I'm going to come back for you. OK? I promise.

Dean

Game’s over, Dean. No more second chances. No more extra lives. Time to say bye bye to Luigi, Mario.

Billie

I told you that roadhouse chili was a bad idea.

Sam

You can't save everyone.

Rufus

I'm worried about my boys.

Bobby

Bobby: Were you ever nice?
Rufus: 1985. Worst year of my life.

You really thought you could double-cross me? Me? You know, I invented the double-cross. Like, literally.

Lucifer

With all due respect, Simmons, I don't think you can handle my rod.

Crowley

No matter how much it hurts, no matter how hard it gets, you gotta keep grinding. And that's how we're gonna win. And we're gonna win. We're gonna save Cas, we're gonna ice the Devil and we're gonna shank the Darkness. And anyone that gets in our way? Well, God help them.

Dean

Supernatural Quotes

You betrayed me? No one in the history of torture's been tortured with torture like the torture you'll be tortured with.

Crowley

At least I don't look like a lumberjack.

Castiel