I just remember I was with two guys. One was like a male model type and the other was an older guy named... Bobby.

Sam

I wish it hadn't come to this. Well, rest assured, when this is all over, I will save Sam, but only if you stand down.

Castiel

Dean: You don't even see it do you. How totally off the rails you are!
Castiel: Enough. I don't care what you think.

I thought you said that we were like family. I believe that too. Shouldn't trust run both ways?

Castiel

I'm Dean, the guy who hit you. I just, uh, I lost control for a minute and I just wanted to say that I'm sorry. I'm real happy you two are both ok. I'm so glad your life can get back to normal now.

Dean

Castiel: Dean, I said I'm sorry and I meant it.
Dean: Thank you. I wish this changed anything.
Castiel: I know. So do I.

Balthazar: Drinking your feelings Sam? I thought that was your brother's bag.
Sam: Stressful times.

Expert on Lovecraft: You know, trench coat: looks like Columbo, talks like Rain Man.

You know, we're not all alike.

Dr. Visyak

Next customer.

Dean

Your chocolate has been in my peanut butter for far too long.

Crowley

Dean: Am I supposed to know who that is?
Bobby: Horror writer? At the Mountains of Madness? The Call of Cthulu?
Dean: Yeah, no. I was too busy having sex with women.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean