Dean: I'll stay here. Hook up with the posse, cause you know me, I'm a posse magnet. I mean I love posse. Make that into a t-shirt.
Sam: You done?

Candy gram for Mongo!

Dean

Yippee ki yay, mother f-

Dean

When you've done this job as long as I have, a giant from the future with some magic brick doesn't exactly give you the vapors.

Samuel Colt

Dean: You know what that is?
Sam: Yeah, it's horse sh-
Dean: Authenticity.

Sam: You can recite every Clint Eastwood movie ever made. Line for line.
Bobby: Even the monkey movies?
Sam: Yeah, especially the monkey movies.
Dean: His name is Clyde.

So we get stuck with Ms. Moneypenny.

Dean

Dean: We'll Star Trek 4 this bitch.
Bobby: I only watched Deep Space 9.
Dean: It's like I don't even know you guys anymore.

Bobby: Either of you jokers ever heard anything about a Phoenix?
Dean: River, Joaquin, or the giant flaming bird?

Titanic didn't suck that bad. Winslet's rack?

Dean

Balthazar really unraveled a sweater over a chick flick?

Dean

Dean: Too soon?
Sam: Yeah, Dean, I'm pretty sure six seconds is too soon.

Supernatural Season 6 Quotes

How do you keep your lawn so green? C'mon Dean, you've never been what I call, Brady.

Yellow-Eyed Demon

It's like chicks specifically dig unavailable guys.

Dean