“Here we go,” Mayim Bialik captioned the above image.

“Knock, knock, knock, thank you… Thank you, apartment 4A, for being a home to so many dreams come true, to so many friendships made," Parsons captioned the above photo on Instagram.

"And thank YOU, ALL of you — yes, YOU, reading this right NOW! As we get ready to tape our final episode tonight, to walk in and out of this apartment door for the last time, it is hard to find the words to articulate what a profound experience this has been."

"But the words ‘love’ and ‘gratitude’ come to mind… so love and gratitude to all of you. ALL of you… ”

“More feelings than words can express,” Galecki shared of his own character's apartment.

“Gonna miss napping next to @missmayim," Sussman shared.

"We nap in adjacent dressing rooms, so we simulated what that would look like if you removed the wall."

"Did I mention that Mayim’s room is also where I’ve had some of my most productive psychotherapy sessions? Thank you Dr. Bialik. ❤️”

“The friends you make along the way… One of the best things about showing up to Stage 25 all these years has been seeing @themelissarauch’s smiling face,” Sussman said of the above photo.

Melissa Rauch said the following:

“While Stuart may have taken up residence in the Wolowitz household @kevsussmantook up residence in a special place in my heart.”

“Do @kaleycuoco and I look like we’re keeping it together?," Sussman wondered in the caption for the above photo.

"Took this right before our final speed read. Before our final taping. Before my final emotional breakdown."

"Gonna miss working with Kaley so much. Sometimes you get to work with an actor that’s so thoroughly in the moment that you can look to them at any time to ground you – Kaley has been that for me for eleven years. ❤️”

“I’m sitting in the set where it all began for me, ten years ago, watching the taping of the final episode of the show," Wheaton shared via social media.

"It’s poetic and heartbreaking and beautiful that my journey with @bigbangtheory_cbs is coming full circle tonight."

"I don’t have the words to properly express my gratitude and love, but I’ll try. To my friends in the cast, crew, and writer’s room: thank you for everything; not just the work and the wonderful experience as an actor, but for welcoming me into your family, and being such a huge part of my life. I’m going to miss you so much. I’m not crying, you’re crying.”

“#SimonHelberg and I have logged so many hours talking about acting and theater and film and everything we’re passionate about and have been blessed to be able to do for a living," he said.

"One of the funniest people I’ve ever met, on screen and off."

"With all the phenomenal success of the show, Simon’s passion for the work has never changed. Still exploring. Still asking questions."

"Still doing spot on impressions of Christopher Walken that make you spit your milk out. Love this guy.”

“You know you work with wonderful and extremely thoughtful people when they celebrate your June birthday along with today’s birthdays (@kunalkarmanayyar @sanctionedjohnnygalecki ) because you won’t be together when it comes around this summer,” Raych shared.

“Final group scene. That’s a wrap," Cuoco shared.

“Goodnight from Stage 25.” Bialik shared.

“Leonard Hofstadter, PhD,” he wrote on Instagram.

“Goodnight, Pasadena," Rauch wrote.