What does Meg turning 18, Peter declaring war on the Amish and the guys going on a road trip to the deep south have in common?

All are featured in the following Family Guy trailer, which debuted at Comic-Con and which previews the season ahead. It premieres on September 25 and, as always, TV Fanatic will be your destination for all photos, recaps, reviews and Family Guy quotes.

Now, back to those darn Amish...

Matt Richenthal is the Editor in Chief of TV Fanatic. Follow him on Twitter and on Google+.