Rest in peace, Brian. Family Guy shocked viewers by killing off this character in November 2013.
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Brian and Stewie head back to 17th century Jamestown on Family Guy. "Life of Brian" is the sixth episode of the show's 12th season.
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Family Guy Season 12 Episode 6 Quotes

Peter: Aren't you supposed to be running?
Chicken: Don't talk to me. You have a bad reputation in the chicken community.

Dammit Brian, you can't die! We were gonna do so many things together! We were gonna become windsurfers! I was gonna be a little better than you, but we were both gonna be good.

Stewie