Sheldon: Looking out at your fresh young faces, I remember when I, too, was deciding my academic future as a lowly graduate student. Of course, I was fourteen. And I had already achieved more than most of you could ever hope to, despite my 9:00 bedtime. Now, there may be one or two of you in this room who has what it takes to succeed in theoretical physics, although it's more likely that you'll spend your scientific careers teaching fifth graders how to make papier-mâché volcanoes with baking soda lava.
Leonard: Oh, good God.
Sheldon: In short, anyone who told you that you would someday be able to make some significant contribution to physics, played a cruel trick on you—a cruel trick indeed. Any questions? ... Of course not. I weep for the future of science