Sheldon: How do I know that you're not manipulating me right now?
Amy: I think if I were manipulating you, you'd be smart enough to see it.
Sheldon: How do I know you're not saying that as part of the manipulation?

Howard: Is that book called Lies I Tell to Get Sex?
Raj: Is that a real book? I would totally read that book.
Amy: Can I borrow it when you're done?

Amy: Y-You'll feel better after you eat.
Sheldon: Okay.
Amy: What-what do you want, like, Thai food? A... a burger?
Sheldon: I don't know!

Sheldon: Amy, mourning the inevitable is a complete waste of time.
Amy: And watching a bunch of goody space movies you've seen hundreds of times isn't?
Sheldon: If we were in a physical relationship, you just lost sex tonight.

Bernadette: This is pretty cool. You don't see too many spherical cakes.
Amy: I wonder why that is.

Bernadette: Girl Sprouts?
Amy: My mom made it up as an alternative to the Girl Scouts. She didn't want me selling cookies on a street corner like a whore.

How could you let him go?!

Amy: I'm stimulating the pleasures of this starfish. I just need to turn it off.
Penny: What happens if you don't?
Amy: Then I have to sit through lunch knowing this starfish is having a better day than I am.

I'm saying, in the spirit of science, what is that little skank's problem?

Sheldon: Did you enjoy my lecture?
Amy: No, and neither did our waiter.

It's a good thing I'm not wearing flag underwear right now because there's about to be a fire.

Sheldon: I have some odd freckles on my buttocks. Can I make an appointment for you to look at them?
Emily: Um... okay, I guess.
Amy: I'm with him three years, nothing. She's with two minutes, and he's taking his pants off.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?