I think this is the Olympics of self-pity.

Watson

I'm telling you right now that you did not kill that woman.

Watson

Watson: I thought a spoonful of sugar might help.
Holmes: I always found a crowbar works better.

Maybe because Wyatt Earp got back into his time machine and disappeared.

Watson

We're not here about the R22 or the improper storage of nutters.

Sherlock

This woman wasn't just murdered. She was rapidly turning into a mummy.

Sherlock

I'm not easily surprised but I do confess that I wasn't expecting this.

Sherlock

Joan: That's the sex blanket.
Sherlock: I've asked you not to call it that.

Sherlock: Wailing Goggle Man alone must burn enough fuel in a year to send a rocket to Mars.
Agatha: "Wailing Goggle Man"?
Sherlock: Yeah, yeah, the Irishman with the songs.
Agatha: Bono. His name is Bono.

Sherlock: She's asked for a donation.
Joan: What, to an environmental group?
Sherlock: To her uterus.

So now you have to have brain damage to want a baby?

Joan

Watson: How do you do it, guess things?
Sherlock: I observe and then I deduce.
Watson: How did you know I was a doctor, you said you could tell from my hands.
Sherlock: Hand, singular. It was soft no calluses.
Watson: How did you know my father had an affair?
Sherlock: Google. Not everything is deducible.

Elementary Quotes

Holmes: Why do you suppose you hate your job so much?
Watson: I don't hate my job.
Holmes: You have two alarm clocks. No one with two alarm clocks loves their job. Two alarm clocks mean it's a chore for you to get up in the morning.

Watson: How do you do it, guess things?
Sherlock: I observe and then I deduce.
Watson: How did you know I was a doctor, you said you could tell from my hands.
Sherlock: Hand, singular. It was soft no calluses.
Watson: How did you know my father had an affair?
Sherlock: Google. Not everything is deducible.