Expert on Lovecraft: You know, trench coat: looks like Columbo, talks like Rain Man.

You know, we're not all alike.

Dr. Visyak

Next customer.

Dean

Your chocolate has been in my peanut butter for far too long.

Crowley

Dean: Am I supposed to know who that is?
Bobby: Horror writer? At the Mountains of Madness? The Call of Cthulu?
Dean: Yeah, no. I was too busy having sex with women.

Submit or die. What are you? French?

Crowley

I'm asking you, Father, one last time. Am I doing the right thing? Am I on the right path? You have to tell me, you have to give me a sign. Give me a sign! Because if you don't I'm going to do whatever I must.

Castiel

Next to Sam, you and Bobby are the closest things I have to family. You are like a brother to me. So, if I'm asking you not to do something, you've got to trust me, man.

Dean

Castiel: Whose Heaven is this?
Raphael: Ken Lay's. I'm borrowing it.
Castiel: I still question his admittance here.
Rapahel: He's devout. Trumps everything.

Bobby: But if we ain't, if there's a snowball of a snowball's chance here, that means we're dealing with a Superman here who's gone darkside. Which means we've got to be cautious, we've got to be smart, and maybe stock up on some Kryptonite.
Dean: [to Sam] This makes you Lois Lane.

Don't worry? What, like Lucifer didn't worry? Or Michael? Or Lillith? Or Allistair? Or Azazel didn't worry? Am I the only game piece on the board who doesn't underestimate those nightmares!?

Crowley

C'mon, dry dung can only be stacked so high.

Castiel

Supernatural Season 6 Quotes

How do you keep your lawn so green? C'mon Dean, you've never been what I call, Brady.

Yellow-Eyed Demon

It's like chicks specifically dig unavailable guys.

Dean