Leonard: When we watch Frosty the Snowman, he roots for the sun.
Sheldon: Excuse me, but the sun is essential for all life on earth. Frosty is merely a bit of frozen, supernatural ephemera in a stolen hat. A crime, by the way, for which he is never brought to account.

Stephen Hawking: You made an arithmetic mistake on page two. It was quite a boner.
Sheldon: No, no ... that can't be right. I-I don't make arithmetic mistakes.
Stephen Hawking: Are you saying I do?
Sheldon: Oh, no, no, no, of course not. It's just, I was thinking.... Oh, gosh, golly, I made a boo-boo and I gave it to Stephen Hawking.
Stephen Hawking: Great, another fainter.

I'd kill my rabbi with a pork chop to be with your sister

Wolowitz

Boldly go, Howard Wolowitz.

Sheldon

I won't say that all senior citizens who can't master technology should be publicly flogged, but if we made an example of one or two, it might give the others incentive to try harder.

Sheldon

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?
Penny: Damn.
Amy: Well, at least, when we do make love, Sheldon won't be thinking about his mother.

Penny: Oh, okay, look. THIS. NEVER. HAPPENED. Do you understand me?
Raj: (nodding)
Penny: Really?! Still can't talk to me?!

Leonard: Well, it seems once again you're caught between a rock and a crazy place.
Sheldon: Oh, I hate when that happens.

Good morning, slut.

Penny

"Sorry" doesn't make up for the fact that I had to make chicken and rice with this vegan guy! Do you know what vegan chicken and rice is? Rice!

Raj

Zack: I see, you were inferring that i'm stupid.
Sheldon: That's not correct. We were implying it... you then inferred it.

Raj: In Avatar, when they have sex on pandora they hook up their ponytails, so we know that their ponytails are like their junk.
Wolowitz: Yeah, so?
Raj: So when they ride horses and fly on the birds, they also use their ponytails...
Wolowitz: What's your point?
Raj: My point is if I were a horse or a bird, I'd be very nervous around James Cameron.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?