Bernadette: Leonard makes you watch that [Game of Thrones] too?
Penny: No, no. I like that show. It's got dragons and people doing it.

Sheldon: Play that funky music, white boy!
Leonard: I'm surprised you know that reference.
Sheldon: What reference?

Sheldon: Would you like to play a physics car game I invented called "I Can't Spy"? It's all the nail biting tension of "I Spy," but the added fun of sub-atomic particles and waves outside the visible spectrum.
Leonard: If it's half as much fun as "One Times Ten to the Fourth Bottles of Beer on the Wall," I'm in.

We won't know if there's equality until female Thor has a baby, and the avengers are cool with her pumping breast milk at work.

Amy

Bernadette: Did she throw anything away?
Howard: Nope. If I find my foreskin, I'm gonna kill myself.

Oh, please. I have ideas all day long. Reverse Sea World, where dolphins are allowed to pet people. A new clothing size in between medium and large, called "marge." Snow White retold from the point of view of Sneezy. Why won't Doc prescribe him something? We finally find out.

Sheldon

Penny: I mean, who even reads Scientific American.
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Okay, then, how about this. Let's invite everyone over to dinner. It'll be like Ma's feeding us one last time.

Howard

While my brother was getting an STD, I was getting a PhD.

Sheldon

Leonard: And we weren't even watching TV! We were watching Netflix like the kids do!
Penny: Yeah! Is it a comedy? Is it a drama? Nobody knows!

Bernadette: A two-hundred dollar R2D2 is a business expense?
Howard: Oh, Bernie. You're gonna have to sound a lot more confident when we get audited.

Leonard: It comes with paints and it's kind of creative and artistic.
Penny: Okay, did you go to the dirty store, or Michaels?

TBBT Quotes

Sheldon: Why do you have the Chinese character for "soup" tattooed on your right buttock?
Penny: It's not "soup," it's "courage."
Sheldon: No it isn't. But I suppose it does take courage to demonstrate that kind of commitment to soup.
Penny: How'd you see it? You said you wouldn't look.
Sheldon: Sorry. As I told you, the hero always peeks.

Sheldon: Nothing more fun than a paradigm shifting evening of science.
Penny: (to Leonard) And you thought it was soaping me up in the shower.