Sheldon: Not that, I understand the mechanics.
Professor Proton: Oh, good, good. Because I have no idea what kids these days are calling their, their parts.
Sheldon: I think they say "junk."
Professor Proton: What is happening to this world?

Let's get me waxed!

Amy

Then it's settled. Amy's birthday present will be my genitals.

Sheldon

Intimacy in any form has been challenging for me, but I'd like to show her how important she is, and it feels like now might be the right time.

Sheldon

For future reference, if I want to watch mean girls, I'll stream on Netflix.

Sheldon

Are you sure? You've never really been with a man. Do you really want to start with one that's 6'7"?

You're inviting him into your home. It's intimate. It's where your underpants live.

Bernadette

Do you sing along with the greatest hits of Elvis Presley with that mouth?

Sheldon

Hey! I was humming. One point for Hufflepuff.

Sheldon

Amy, I excel at many things, but getting over you wasn't one of them.

Sheldon

Sheldon: Can you sing "Soft Kitty"?
Penny: What?
Sheldon: My mom used to sing it to me when I was sick.
Penny: I'm sorry honey, I don't know it.
Sheldon: I’ll teach you. [Singing] Soft kitty, warm kitty, little ball of fur. Happy kitty, sleepy kitty, purr, purr, purr. Now you.

No one calls me Moon Pie but Meemaw!

Sheldon

TBBT Quotes

I just gave you my virginity, woman. Cool your jets!

Sheldon

Penny: Leonard, sweetheart, you twisted your ankle playing Scrabble.
Leonard: I got a triple word score with a double letter Q. If that's not a time to bust out the Scrabble dance, what's the point of having one?