Amy: I thought you were taking a break from women to focus on your career?
Raj: Oh, grow up.

Bernadette: What if she likes the people who work there more than us?
Howard: She already likes soap bubbles more than us.

My pants are missing, I don't remember anything. Penny, this is your youth, what do I do?

Sheldon

You know, I felt the same way about the spork. Solids and liquids handled by one utensil, that'll never work. Spoiler? Works.

Sheldon

Uh, oh. Someone's got two dates to the nerd prom.

Penny

Guys before this gets ugly, remember, the winner gets Sheldon.

Raj

Amy: I had a feeling you were using the wrong computational model, but I didn't say anything 'cause you're so sensitive.
Sheldon: Just because I'm easily bothered by light, heat, smell, sound, and the way birds look at me does not mean I'm sensitive!

Bernadette: Look, Raj just gets along with women.
Leonard: I know, but he was my friend first. It's like she's stealing him and they're having the best time doing all their dumb girly stuff together.
Howard: You sure you don't fit in? You sound like a catty bitch to me.

Amy: Number three, to avoid getting frustrated, we take built in breaks and award our successes with a small treat.
Sheldon: Oh that sounds fun. Now we're talking about real treats, right? Not Bible verses like my mother used to give me.

Leonard: Anyway, I figured I can hang out with my friends and have fun too.
Bernadette: Well if your idea of fun is riding in a minivan to Target for diapers things are about to get nuts.

Amy: Wait, are you saying if we combine my experiment with your calculations, we can determine the precise moment in time when the wave function collapses?
Sheldon: It could be the most inspired combination since I mixed red Icee into my blue Icee. It was like drinking 2/7 of the rainbow.
Amy: Sheldon, this is really interesting.
Sheldon: Yeah and this one won't stain my teeth purple.

Sheldon: Gentlemen, the most interesting thing just happened with this spoon.
Howard: Unless it was singing "Be Our Guest," I doubt it.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?