Leonard: That's you having sex with a guy in the top half of a Chewbacca costume. Comic Con?
Alice: You'd think, but no.

It's a rough month when Halloween and PMS hit at the same time.

Penny

Howard: Did we just see you pick up a girl in a comic book store?
Stuart: 'Cause if you did, you get your picture up there on the wall on the Wall of Heroes.

Leonard: Oh. Watch out, Sheldon. This little boy Casper is a g-g-g-ghost!
Sheldon: Droll.
Howard: Not as droll as a grown man passed out in a puddle of his own urine.
Leonard: That was pretty droll. With a hint of ammonia.

[reading on wall] "See you in hell Sheldon."
The most frightening thing about that is the missing comma.

Sheldon

Hear that? Girl trouble. Turns out we were both wrong on that front.

Sheldon's mom

Raj: None of our gods have abs like that.
Howard: Yep, that's the last Jew who did sit-ups. And look where it got him.

Amy: Sheldon, is it possible that your foul mood -- or, to use the clinical term, bitchiness -- is because your mother isn't making you a priority?
Sheldon: No. Or, to use the clinical term: "nuh-uh."

Well, I can't spend $12,000 on a handbag, but it's free to look upon those who do with righteous condemnation.

Sheldon's mom

Sheldon's mom: I bet your mom is really proud of you.
Howard: Nope. She says if I don't back out, she's gonna go on a hunger strike. It'd take years before she'd be in any kind of danger, but still....

I couldn't find you guys, so I bought six new friends. Sadly, three are dead.

Raj

Oh, they don't always get to ride the roller coaster. Sometimes they only get to spin the teacups.

Penny

The Big Bang Theory Season 5 Quotes

You can't blame yourself. When your prefrontal cortex fails to make you happy promiscuity rewards you with the needed flood of dopamine. We, neurobiologists, refer to this as the skank reflex.

Amy

I feel like two totally different people. Dr. Jekyyl and Mrs. Whore.

Penny