The two of you need to get your women in line!

Sheldon

I'm just saying, second base is right there.

Amy

Amy: At this moment, I find myself craving human intimacy and physical contact.
Sheldon: Oh, boy.

[knock] Amy. [knock] Amy. [knock] Amy.

Leonard

Sheldon: I can't seem to get in touch with Amy. I tried e-mail, video chat, tweeting her, posting on her Facebook wall,texting her, nothing.
Leonard: Did you try calling her on the telephone?
Sheldon: The telephone. You know, Leonard, in your own simple way, you may be the wisest of us all.

Sheldon: New topic: women. Delightfully mysterious or bat-crap crazy?

Sheldon, sometimes you forget, I'm a lady. And, with that comes an estrogen-fueled need to page through thick glossy magazines that make me hate my body.

Amy

Bazinga, punk. Now we're even.

Sheldon

Leonard: Damn it, I can't. I can't do this.
Alice: Is it my tongue stud? 'Cause if that freaks you out, you're in for a real surprise later on.

Well ... they say at the end of your life, you regret the stuff you didn't do more than the stuff that you did. And, I'm pretty sure Alice is the stuff I want to do.

Leonard

Alright, so the topic at hand is sexual fidelity. Probably won't be relying on Seuss here. Although 'One Fish, Two Fish, Red Fish, Blue Fish' might be surprisingly applicable.

Sheldon

I tried to scare an Indian with a snake. Come on, Cooper, you're better than this.

Sheldon

The Big Bang Theory Season 5 Quotes

You can't blame yourself. When your prefrontal cortex fails to make you happy promiscuity rewards you with the needed flood of dopamine. We, neurobiologists, refer to this as the skank reflex.

Amy

I feel like two totally different people. Dr. Jekyyl and Mrs. Whore.

Penny