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- Webber steps down as Chief and is replaced by Owen, pissing off Bailey.
- The fifth year residents tackle their first solo surgeries; Meredith breezes through, Alex panics, Cristina forgets, and Jackson never touches his patient.
- Cristina and Owen share some awkward moments and get food poisoning together.
- Meredith and Derek fight about trust; he can’t trust her at work but will not walk away from their marriage.