Vanessa: Serena, I know you like him, but as your friend, Julian is the most self-absorbed pompous person I have ever met. All he does is go on and on about classic movies and it's totally annoying.
Serena: You were keeping up with him pretty good there.
Vanessa: Yeah. And I'm totally annoying.

Serena: I'm here on a rather pathetic mission. I'm boyfriend snooping.
Vanessa: I see.
Serena: It's not something I'm proud of, but I don't know what else to do. Something's going on with Dan, I thought I knew what it was but I don't. I was wondering if he said anything to you.
Vanessa: No he didn't. I'm sorry.

Serena: I figured if he would've told anyone, he would've told you.
Vanessa: Whatever it is, I'm sure he'll tell you. Dan's not exactly one for keeping secrets.
Serena: I used to think that, but now I don't know anymore.

Penelope: Oh, hello, weird documentary girl.
Vanessa: Oh, hello, sad Blair wannabe.

[to Blair] Now that we've established that I own you, you have six hours to get a thousand signatures and make sure they're legible. Have fun!

Vanessa: I can make you help me you know.
Blair: Oh, it makes jokes too!
Vanessa: Everyone knows you and Marcus broke up, but no one knows why. [shows picture]
Blair: Even you wouldn't stoop that low.
Vanessa: Blackmail works so well for you ... maybe I'm missing out!

Nate: You crash the party, and tell me to break it off with Catherine. Then you pull a 180 and tell me to stay with her. And then you just bolt. I mean, did I do something? Or... what happened?
Vanessa: I'm late.
Nate: Oh so that's it. We're not even friends now?
Vanessa: We were never really friends, Nate.

Vanessa: Nate? What are you doing here?
Nate: You haven't returned my phone calls.
Vanessa: I've ... been busy.

Dan: I can't believe Nate Archibald is a gigolo.
Vanessa: You can't tell anyone!
Dan: Who? Who would I tell? Except everyone I've ever met. [pauses] I won't.

Dan: Why'd you tell him to stay with that woman? Y'know, I thought you liked him.
Vanessa: I do. That's why I did it.
Dan: I don't understand.
Vanessa: She told me that if Nate left her, she would go to the FBI and tell them where Nate's dad is hanging out. So ... I really didn't have a choice.

Nate, you have to end this for yourself. Forget about what I said before. You are better than this. I'll be here when you get back.

Vanessa: I don't believe this. I kept telling myself you were different than Blair and all the others, but you're just as bad!
Nate: It's not that simple, okay?
Vanessa: Are you sleeping with that woman?
Nate: Yes.
Vanessa: Is that the reason you keep canceling on me?
Nate: Yes, but...
Vanessa: No, Nate, there are no buts. You lied to me and you're sleeping with some Mrs. Robinson. And while on the Upper East Side that might be totally normal, I didn't sign up for some love triangle with you and somebody's mom!

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.