Simmons: You know how boys can be with their robots!
Daisy: Actually, I really don't.

I'll play you music when I can. Studies show that listening to music increases dopamine levels by nine percent.

Aida [to May]

First of all, that thing is not a she. It's a damn robot. And second of all, what is the matter with you two chuckleheads? Have either one of you seen a movie in the last thirty years? The robots always attack.

Mack

It's all right, Agent Simmons, I won't bleed out. The synthetic blood is mostly for appearances' sake.

Aida

Director Mace: In case you haven't noticed, Phil, we're not a team that trusts. We're not a team at all.
Coulson: You may be right. But we better become one if we're going to stop Eli Morrow from blowing up half of Los Angeles.

That's the most ridiculous idea I've heard all day, and I've had a long day.

Mack

Eli: I can create a city out of nothing. I can cover it in volcanic rock. Robbie, I am becoming a god.
Robbie: You better be. Because the devil is coming for you.

Okay, forget about the fact that I was mildly attracted to her. That totally goes against the Sekovia Accords. Doesn't anyone remember Ultron?

Director Mace [on Aida]

Mack: It's not a mask, it's a balaclava.
Robbie: I thought that was a dessert

Coulson: When this is over, it's time. We're cracking that bottle.
May: You won't have to twist my arm.
Coulson: I wouldn't dare. You'd whip my ass.

I don't like magic. Or clowns. Clowns with knives and magic. In the dark.

Fitz

Give me my vengeance on Eli. Settle my score, and I'll settle yours. All of yours.

Robbie [to Ghost Rider]

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.