What is one life compared to thousands of innocent ones?

Odin [to Sherlock]

Odin: I don't suppose you'd mind closing the door.
Sherlock: I don't suppose you want to confess to all the murders you've sponsored.

You haven't touched your dinner. You don't think it's poisoned, do you?

Sherlock [to Annie]

Reichenbach isn't the only person with friends in high places. And I would say mine are further up the mountain than his.

Morland

Battling global criminal enterprises is an area in which I have some expertise. Shall we attack him together?

Morland [to Sherlock]

You're referring to old data. I bring you new data. Won't you consider it?

Sherlock [to Odin]

In our business, almost everyone we meet is unsavory.

Durah

Actual city murders must not wait.

Sherlock [to Joan]

I brought a present. Shall we open it together?

Odin [to Sherlock and Joan]

Ollie's a magnificent animal, isn't he?

Sherlock

Ollie would make a good canine canary in the coal mine.

Sherlock [to Marcus]

Sherlock: Kind of ironic, a weed-sniffing dog fostered by someone who sells the stuff.
Marcus: I don't know about ironic, but I don't think it's a coincidence.

Elementary Quotes

Holmes: Why do you suppose you hate your job so much?
Watson: I don't hate my job.
Holmes: You have two alarm clocks. No one with two alarm clocks loves their job. Two alarm clocks mean it's a chore for you to get up in the morning.

Watson: How do you do it, guess things?
Sherlock: I observe and then I deduce.
Watson: How did you know I was a doctor, you said you could tell from my hands.
Sherlock: Hand, singular. It was soft no calluses.
Watson: How did you know my father had an affair?
Sherlock: Google. Not everything is deducible.