Sam: You can recite every Clint Eastwood movie ever made. Line for line.
Bobby: Even the monkey movies?
Sam: Yeah, especially the monkey movies.
Dean: His name is Clyde.

So we get stuck with Ms. Moneypenny.

Dean

Dean: We'll Star Trek 4 this bitch.
Bobby: I only watched Deep Space 9.
Dean: It's like I don't even know you guys anymore.

Bobby: Either of you jokers ever heard anything about a Phoenix?
Dean: River, Joaquin, or the giant flaming bird?

Titanic didn't suck that bad. Winslet's rack?

Dean

Balthazar really unraveled a sweater over a chick flick?

Dean

Dean: Too soon?
Sam: Yeah, Dean, I'm pretty sure six seconds is too soon.

Sam: You totally Butterfly Effected history.
Dean: Dude. Dude. Rule 1: No Kutcher references.

Sam: So you save the cruise liner because...
Balthazar: Because that god-awful Celine Dion song made me want to smite myself.

Balthazar: I hated the movie.
Dean: What movie?
Balthazar: Exactly.

Accidents don't just happen accidentally. You know what I mean.

Dean

You two gonna stand there like the ugly girl at the prom or are you going to pitch in?

Bobby

Supernatural Quotes

Boy, three bedrooms, two baths, and one homicide. This place is going to sell like hotcakes.

Dean

Dean: Do I know you?
Becky: No, but I know you.