Dwight Yoakam guest stars here on Wilfred. It's a scene from "Doubt."
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This is a typical interaction for Wilfred and Ryan. The latter is a bit freaked out by the former.
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Wilfred Season 1 Episode 11 Quotes

He says I won't be able to adjust to a new culture. Excuse me, but I was the one who was willing to live in the Valley.

Kristen

What did you do with my hair? I distinctly remember leaving it right here, all over the place.

Wilfred