ADDISON: "What they're doing is not about love, Derek! Well, it's like you."
DEREK: "Excuse me?"
ADDISON: "How you pretend to love me, but really you're just using me to fill this need you have to be a good guy."
DEREK: "Now's not the time to talk about this. We'll talk about this later."
ADDISON: "What, you walk away? That's all I get?"
DEREK: "Just calm down, please."
ADDISON: "Wait, what, you're not going to yell at me? Call me names? Or, I don't know, ignore me in an elevator?"

ADDISON: "Good work, Dr. Karev. The baby's going to live."
ALEX: [walks away] "Yeah... without a mother."

ADDISON: "You would not believe the day I had. I went out of my way to give a patient exactly what she wants only to have it explode in my face. And don't even get me started about Alex Karev."
DEREK: "Get in the shower."
ADDISON: "What?"
DEREK: "You wanna have hot sex? Get in the shower!"

ALEX: "The road to hell is paved with good intentions."
ADDISON: "Dr. Karev, you did such a good job today that I'm going to talk to Dr. Bailey and have you assigned to my service."
ALEX: "What? For how long?"
ADDISON: "For as long as I want. Your ass is mine until I say otherwise. Congratulations."

ADDISON: "Option one, I go home. End of story. Option two, I could apologize, you could forgive me, come home, but you could still bring it up to use against me whenever we argue."
DEREK: "Are you trying to be funny?"
ADDISON: "Satan has a sense of humor."
DEREK: "Is there a third option?"
ADDISON: "I don't know what the third option is. I just know I still love you."

DEREK: "Maybe you should've thought of all this before you gave chief to Burke and invited Satan to Seattle."
RICHARD: "Satan?"
ADDISON: "Good morning Richard, like the hat."
DEREK: "Satan speaks."
ADDISON: "Actually, I prefer to be called ruler of all that is evil. But I will answer to Satan."

DEREK: [answers phone] "Hello? Hi. Yeah, yeah." [to Addison] "It's about Doc. No, I'm here... I can pick him up this morning. Sure, I-"
ADDISON: [grabs phone] "Hi, Dr. Dandrige? Listen, we're gonna have to call you back becasue we're trying really hard to have some decent sex here." [hangs up]
MEREDITH: [silence]

ADDISON: "Thanks."
DEREK: [laughs] "Your thanking me for the most boring sex ever!?"
ADDISON: "I didn't know what else to say."

ADDISON: "Dr. Karev-"
ALEX: "Sorry. I don't do vagina. Not as a doctor anyway."
ADDISON: "Oh, back talk, that buys you a case."

"Sometimes people do desperate things to get someone's attention. But there are two sides to every story."

DEREK: "Addison and I are over, Adele."
ADDISON: "Oh, it's not like we're divorced."
DEREK: "We're practically divorced."
ADELE: [to Addison] "You've had counseling?"
DEREK: "We've had adultery. That was enough."

ADDISON: "We got successful, you and me. We got busy and we got lazy. We didn't even bother to fight anymore, Derek. Mark was there and I missed you and now I'm sorry. I'm more sorry than you could possibly imagine, but at least I'm talking to you about it."
DEREK: "I'm a sink with an open drain, Addie."

Grey's Anatomy Quotes

When we say things like "people don't change" it drives scientist crazy because change is literally the only constant in all of science. Energy. Matter. It's always changing, morphing, merging, growing, dying. It's the way people try not to change that's unnatural. The way we cling to what things were instead of letting things be what they are. The way we cling to old memories instead of forming new ones. The way we insist on believing despite every scientific indication that anything in this lifetime is permanent. Change is constant. How we experience change that's up to us. It can feel like death or it can feel like a second chance at life. If we open our fingers, loosen our grips, go with it, it can feel like pure adrenaline. Like at any moment we can have another chance at life. Like at any moment, we can be born all over again.

Meredith

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)