Bree: You cannot let your mother move into this neighborhood. It's filled with junkies and whores.
Orson: And we'll owe them all an apology.

Keith's mother: I promise to be on my best behavior.
Bree: I know you will. Because, as Keith told you, I have guns.

Karl: You're supposed to be catering a wedding.
Bree: Yes, clearly this is my fault. (the woman raises up) Courtney?
Courtney: I'm so sorry, Bree.
Bree: Really, Karl, my yoga instructor?
Courtney: No charge for next month, okay?
Bree: Like I'm keeping you! Get the hell out of my house.
Karl: She... she's going.
Bree: I'm not talking to her!

Bree: I am so tired of feeling like the worst mother who ever lived.
Andrew: You're not. There's grandma.
Bree: I just... I've tried so hard to set a good example. I've done the best I could to teach you kids right from wrong. Why isn't it taking?
Andrew: It took. I mean, we know the difference between right and wrong. We just chose wrong.
Bree: Why?
Andrew: Sometimes, when you push a kid really hard to go one way, the other way starts to look more entertaining.
Bree: (smiling) You're awful.
Andrew: I know. I blame shuddy parenting.

Bree: Honey, do your hands still tremble when they touch me?
Rex: No. But come on, we've been married eighteen years.
Bree: Yes we have. And you still don't know when I need you to lie

Good friends offer to help in a crisis; great friends don't take no for an answer

Rex: I can't believe you tried to kill me.
Bree: Yes, well, I feel badly about that

Bree: If I'm gonna break a commandment, I don't want it to be for a quickie on this couch.
Karl: Who said quickie? I've got 40 minutes before my 10 o'clock. And thou shalt get sweaty.

Rex: For gods sake, you promised to be supportive.
Bree: What do you want me to say? My husband likes to wear metal clamps around his nipples. Hooray?

For God's sake Phyllis, don't you ever worry about dehydration?

George: He cheated on you. You said you were going to hate him forever.
Bree: You shouldn't listen to a woman who's just had her heart broken. We tend to lie

John: Mrs. Van De Kamp.
Bree: Hello, John. I'm sorry to drop by on you, unannounced. Do you have a moment?
John: Sure. So, what can I do for you?
Bree: Well, I'll tell you. My daughter is planning on giving you her virginity and I would consider it a personal favor if you wouldn't take it

Desperate Housewives Quotes

Dr. Barr: Hey there. I was surprised to hear you wanted a session.
Bree: Well, there's nothing like being tied to a bed to change a girl's mind.
Dr. Barr: What do you wanna talk about?
Bree: Anything at all. As you said, I...I have a lot of issues.
Dr. Barr: Well, I assumed as much when you told the ridiculous story about your daughter running off with a murderer.
Bree: Saw right through that, did ya?
Dr. Barr: Well, I'm a trained professional, Bree. The human mind is my playground.
Bree: Well, I'm glad that you're having fun.

(to dead body) "Tu me manques, Monique" ("I Miss You Monique").

Orson