Graveyard Caretaker: Tell me, Agent Nugent, have you thought about where you might like to spend eternity?
Dean: All the damn time.

Dean: You know I finally get why you and dad butted heads so much. You two are practically the same person. I mean I worshipped the guy, y'know: I dressed like him, I acted like him, I listened to the same music. But you are more like him than I will ever be. I see that now.
Sam: I'll take that as a compliment.
Dean: You can take it any way you want.

Castiel: We need to talk.
Dean: I'm dreaming, aren't I?
Castiel: It's not safe here... someplace more private.
Dean: More private? We're inside my head.
Castiel: Exactly. Someone could be listening.

Dean: Cas you okay?
Jimmy: Castiel - I'm not Castiel. It's me.
Sam: Who's me?
Jimmy: Jimmy - my name's Jimmy.
Dean: Where the hell is Castiel?
Jimmy: He's gone.

Dean: What were you doing anyway?
Sam: I went for a Coke.
Dean: Was it a refreshing Coke?

Congrats, Sammy. You just bought yourself a benchwarmer seat to the Apocalypse.

Dean: Well, it's about time. I've been screaming myself hoarse out here for about two and a half hours now.
Castiel: What do you want?
Dean: Well, you can start with what the hell happened in Illinois?
Castiel: What do you mean?

If you walk out that door, don't you ever come back.

Dean: Yeah, well, I'll tell you one thing. At this point, I hope he's with Ruby.
Bobby: Why?
Dean: 'Cause killing her is the next big item on my to-do list.
Bobby: I thought you were on call for angel duty.
Dean: I am on call, in my car, on my way to murder the bitch.

Dean: I need you to take me to see Sam.
Castiel: Why?
Dean: There's something I have to talk to him about.
Castiel: What's that?
Dean: The BM I took this morning. What's it to you? Make it snappy.

What's this supposed to be, the suite life of Zach and Cas?

Dean: Do I know you?
Becky: No, but I know you.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean