Derek: How is Meredith, anyway?
Cristina: Fine.
Derek: She's always fine. That's her problem.
Cristina: We're fine people. We do fine. We're fine.

[in flashback]
JOE: "Straight tequila? Really? You are going to be sorry in the morning."
MEREDITH: "I'm always sorry in the morning. But tomorrow is my first day at work, so keep 'em coming."
DEREK: "Double scotch, single malt please. [To Meredith] So, is this a good place to hang out?"
MEREDITH: "I wouldn't know, never been here before."
DEREK: "You know what? I haven't either. First time here. I'm new in town. Never been to Seattle. New job soon. Ah, you're ignoring me."
MEREDITH: "Trying to."

CRISTINA: [to Mer, but everyone hears] "Are you pregnant?"
ADDISON: [to Derek] "An adulterous love child?"
DEREK: "Goes along with an adulterous sociopath."

DEREK: "Doesn't look like there's any nerve damage. There shouldn't be any long-term effect. I'd wait a few weeks before I tested it out, though."
MEREDITH: "Funny. You're a funny man."
DEREK: "I just didn't know you two were dating."
MEREDITH: "You knew it would happen eventually."
DEREK: "Eventually feels a lot different than actually."
MEREDITH: "Yeah, I guess it does."
DEREK: "It's surprisingly painful."
MEREDITH: "It gets better."
DEREK: "Does it?"

MEREDITH: "Hey."
DEREK: "Well, hey."
MEREDITH: [tries not to laugh] "So, you picked up Doc?"
DEREK: "Yeah, he's home."
MEREDITH: "He seems to be doing better."
DEREK: "Yeah, he's... he's doing good."
MEREDITH: [laughs] "I'm not laughing at you."
DEREK: [laughs] "No."
MEREDITH: "It's just, you know... bad sex isn't the kind of thing that wives want announced to dirty-ex-mistresses."
DEREK: "You're not the dirty ex-mistress. You're a friend. She's your friend. I'm your friend. We're all friends."
MEREDITH: "But you didn't tell her."
DEREK: "No." [smiles] "So how's your day going?"

DIVORCE LAWYER PATIENT: "Any of you are looking to get out of a bad marriage?"
GEORGE & IZZIE: [smirking] "No."
DIVORCE LAWYER PATIENT: "Dr. Shepherd?"
DEREK: "Yes. No!"

DEREK: "I don't want to be the guy that killed Bailey's husband."
PRESTON: "I don't want to be the guy who kills us all."

Meredith: Remember when I was dead? Before I went in that water everything was so ... complicated. Hard. and then you pulled me out of the water ... and I came back to life. for a moment everything was so clear. As if the water had washed everything clean. Do you remember that?
Derek: I do.
Meredith: Me too.

Derrick: Yang, where's Meredith?
Cristina: I don't know, they fired her. Maybe she's putting anthrax in Karev's locker.

We are throwing Bailey under the bus.

RICHARD: "Bailey's back."
DEREK: "Bailey's back?"
RICHARD: "Yes."
DEREK: [Peers through the window, then turns back] "Yes she is, and her cervix is being examined by my wife, which is a visual that I will never get out of my head."

IZZIE: [to Alex] "You are hateful! Hateful! Hateful, arrogant, lazy... hateful man! Hateful!"
DEREK: "Well, never a dull moment here at Seattle Grace. Scalpel?"

Grey's Anatomy Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Sexual sorbet? Hahaha! I love it.

Bailey