You know, people say the Soyuz capsule was a lemon. But, hey, that baby got me to space and back.

At least my mother made her boyfriend climb out the window.

Howard: Attention people of Earth: Tonight, there will be two moons in the sky.

They left dogs up here in the 60s.

Howard's mother: Speak up!
Howard: From now on she's the only woman who can yell at me!

Howard: There's fuel leaking and we're still gonna go?
Cosmonaut: Don't lose your Fruit Loops, Fruit Loops.

Sheldon: He asked her during coitus.
Howard: Did he get down on one knee or were you already there?

No! When I eat Fruit Loops the other astronauts make fun of me.

Quick question. I missed it in the briefing. How much urine do these suits hold?

Bernadette's father: You go up to that space station and you make me proud.
Howard: Um, okay.
Bernadette's father: You got a problem with that?
Howard: All right, look, I'm going to level with you. I'm terrified about going into space. What if I don't make it back?
Bernadette's father: It's gonna be okay, son.
Howard: You really think so?
Bernadette's father: Of course. A pretty girl like Bernadette ... she'll find a new guy.

Howard: Let me explain the difference between you and me. You watch 'Star Trek'; I live it.
Raj: Oh, please, I don't remember the episode of 'Star Trek' where the guy never goes to space and brags about it in a tuxedo store.
Howard: Make all the jokes you want. There is only one of us here brave enough to almost do what I almost did.

Yes! Thank you! Oh! Oh ... I'm not gonna die in space! I'm gonna die the way God intended in my late 50s with a heart full of pastrami.

TBBT Quotes

I just gave you my virginity, woman. Cool your jets!

Sheldon

(Singing) Thor and Dr Jones, Thor and Dr. Jones. One plays with lightening, the other plays with bones.

Howard and Raj