Bernadette: Are those Russian rockets safe?
Howard: Well, I mean, safe as it can be when it was build by the good folks who brought you Chernobyl.

Raj: Whatever, dude. She kissed me.
Howard: It might've been on your lips but it was my kiss.
Raj: Oh, fine, let's agree she kissed both of us.
Howard: Okay.

Raj: Okay, I'm going to play it cool. Tell her, "Maybe. Whatever, babe."
Howard [translating in sign language to Emily]: He'll text you.

Leonard: See, this is the good thing about having a girlfriend 9,000 miles away I can spend my nights doing whatever I want.
Howard: You mean playing nerd games with us and then taking a suspiciously long shower?
Leonard: Maybe.

Howard: Can you believe grown men sit around and play with toy trains?
Bernadette: That's pretty big talk for a man with a closet full of magic tricks at his mother's house.

Howard: This may be hard for you to hear, but when I say "honey," I mean my fiancee.
Raj [whispers into Howard's ear]
Howard: Yeah, well, now it means her.

Bernadette: I'm not going to live with your mother. Not now. Not ever.
Howard: Somebody, obviously, has some mommy issues.

Bernadette: I was head-hunted by a big pharmaceutical company. They're going to pay me a buttload of money!!
Leonard: Bernadette, that's great!! Howard, do YOU make a buttload?
Howard: Better than what YOU got a buttload of!

....I volunteered for the premature ejaculation project. I mean, it's not like either one of us has heart disease.

Bernadette to Howard

Howard: You gotta like this. The girlfriend, the ex-girlfriend bonding over your rooty-tooty stinky booty.
Leonard: Kill me.
Sheldon: It wouldn't help. The human body is capable of being flatulent for hours after death.

Howard: You gotta like this: the girlfriend.....the ex-girlfriend, bonding over your rooty-tooty stinky booty?
(all but Leonard laugh)
Leonard: Kill me!
Sheldon: It wouldn't help. The human body is capable of being flatulent for hours after death.

Whereas Jewish mothers take a casual la-dee-dah approach to their sons.

TBBT Quotes

Sheldon: Are you still mad about the sperm bank?
Leonard: No!
Sheldon: Do you want to hear an interesting thing about stairs?
Leonard: Not really.
Sheldon: If the height of a single step is off by as little as two millimeters most people will trip.
Leonard: I don't care—two millimeters?! That doesn't seem right.
Sheldon: No, it's true! I did a series of experiments when I was twelve; my father broke his clavicle.

Penny, there's only one cookie with something in the middle that solves life's problems, and that's an Oreo. Or a Nutter Butter, if you're in a pinch.

Sheldon