Meg: There's no factory?
Stewie: Ha! Very good, fat man! We follow the Pied Piper of Hamsteak to the Gates of Oblivion, and look what it's brought us! We're finished! We're done! Game over, man! Game over!

Peter [about a handbag]: Oh I love you sweety. What are they like 10 bucks?
Meg: More like eleven...hundred.
Peter: Heh, you wished I loved you that much

Old Lady: What a precious little boy.
Meg: That's my ..uh, uh.. son.
Old Lady: Your son? But you're just a baby yourself. Henry, give the little skank a nice tip

Lois: I'm so worried about your father.
Chris: You mean because he's a borderline alcoholic?
Lois: No. Mommy's made peace with that.
Chris: Oh, cause he's got a lump on his booby!
Lois: Chris, that's a terrible word! "Booby."
Meg: Mom, Debbie Miller's dad had a lump on his breast, and he turned out okay.
Lois: Really? Who's Debbie Miller?
Meg: A girl I just made up

Meg: You could kill all the girls who are prettier than me.
Death: Well, that would just leave England

Peter: Look I've had a good life and you can always be proud of your father in all of his accomplishments.
Meg: What accomplishments?
Peter: Go to your room

Peter: Mr. Weed said whoever comes up with the best idea for the big christmas toy gets a huge bonus!
Chris: Why don't you invent the frisbee, dad? That's an awesome toy!
Meg: The frisbee's already been invented.
Chris: Then how come I've never heard of it?

Meg: I don't get it, mom, if you're so mad at dad for wrecking your show, why did you come to opening night?
Lois: I came because I love the theater. I mean, if I just came here to enjoy watching your father be humiliated when this asinine spectacle of his is ridiculed by everyone in town, what kind of person would I be?
Chris: A bitch

Lois: Meg, Could you please change Stewie for me?
Meg: Fine. But if a boy calls, please don't tell them I'm wrist deep in poopy

Meg: That's it, I want those cameras off!
Chris: Fourth wall, You're breaking the fourth wall!

Chris: Okay, Meg. I'm thinking of another word. This time it's definitely not kitty. Can you guess what it is?
Meg: Is it kitty?
Chris: Ahh! Get out of my head! Get out of my head?

Meg: Mom, can I turn the heat up?
Lois: Don't touch the thermostat, Meg. Your father gets upset.
Meg: Come on. This thing goes up to 90.
[Meg adjusts it a little, and Peter suddenly comes into the room]
Peter: Who touched the thermostat?
Meg: God, how does he always know?
Peter: Brain implant, Meg. Every father's got one. Tells you when the kids mess with the dial.
Guy: My thing went off! Your thermostat okay?

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire