Penny: Can I ask you a question?
Sheldon: Given your community college education, I encourage you to ask as many as possible.

Penny: OK. Well, then, there's a couple of things you should probably know.
Sheldon: I have a master's degree and two doctorates. The things I should know, I do know.

Penny: You have nice hair.
Amy: Are you a homosexual?
Penny: No!
Amy: Would have been more flattered if you were a homosexual.

Sheldon: As a native Texan, I must say that I've never heard the phrase "yee haw" used in quite that context.
Penny: Oh God.
Sheldon: "Oh God." That I've heard on multiple occasions.

Sheldon: This is for you
Penny: Ice cream?
Sheldon: I've been familiarizing myself with female emotional crises by studying the comic strip, "Cathy." when she's upset she says, "ack" and eats ice cream.
Penny: Ack.
Sheldon: If you were a cat, I would have brought you lasagna.

Leonard: If my PE teachers told me this is what I was training for I would have tried a lot harder.
Penny: Do or do not, there is no try.
Leonard: Did you just quote Star Wars?
Penny: I believe I quoted Empire Strikes Back.
Leonard: Oh my God. I'm lying in bed with a beautiful woman who can quote Yoda.

Penny: So what do you say, Sheldon, are we your X-Men?
Sheldon: No, the X-Men were named for the "X" in "Charles Xavier." Since I am Sheldon Cooper, you will be my "C-Men."

Leonard: We think we can help you with your stage fright.
Sheldon: Oh, I doubt that. I haven't figured out a way, and I'm much smarter than all of you.
Penny: Yes, buy you're not smaller than all of us put together.
Sheldon: I'm sorry, that is what I meant.

Penny: I once got a pretty big honor in high school, and I was terrified about appearing in front of a big crowd, but I went through with it, and you know what? The world looked pretty darn good sitting on a haystack in the back of a Ford F-150 as a member of the corn queen's court.
Sheldon: Thank you. I'll bear that in mind if I'm ever nomianted for the hillbilly peace prize.

Okay, I'm just to go home and make a grilled cheese sandwich and window shop on eHarmony.

Penny: Who's Adam West?
Sheldon: Who's Adam West!? Leonard, what do you talk about after the coitus?
Wolowitz: My guess is "four minutes, a new record!"

Penny: Sheldon's in jail.
Leonard: What'd he do?
Penny: The same crap he normally does, except to a judge.

TBBT Quotes

Sheldon: Is anyone else troubled by the Spider-Man theme song?
Leonard: Why would it trouble you? It's like your third favorite cartoon theme song.
Sheldon: It is, right behind [Sheldon sings "Inspector Gadget" and "Teenage Mutant Ninja Turtles" theme songs]
Sheldon: However, the Spider-Man lyrics posit that Spider-Man's Spider-Man does whatever a spider can.
Howard: Yeah, so?
Sheldon: I can think of many things that Spider-Man can't do that a spider can. One crawl in your ear and die, two legally leave Guatemala without a passport, and three have sex with a spider.

I was expecting applause but I suppose stunned silence is equally appropriate.

Sheldon