Stewie: Lee writes: "Dear Family Guy, was your show based on anything?" That's a great question, Lee. In fact, Family Guy is based on an American television series called The Simpsons.

Peter, Peter! There's so much doodie in here.. I can't take it anymore.... I haven't eaten in four days cause... I just can't fit anymore in there. Help me.

A perfectly normal little boy! Who just happens to be a transvestite! Which ... begins with the letter T.

Stewie [on the phone]: You're the new housekeeper aren't you?
Consuela: Si.
Stewie: I don't want to point fingers but I'm missing about thousand dollars of play money.
Consuela: I take.
Stewie: What? You took it?
Consuela: Si.
Stewie: Then give it back.
Consuela: Come get it, bitch.

Brian [at mom's funeral]: Say something.
Stewie: What?
Brian: Just say something please.
Stewie: For god's sake. Um... "Yea, and God said on to Abraham, 'You will kill your son Isaac'. And Abraham said, 'I can't hear you, You'll have to speak into the microphone.' And God said, 'Oh, I'm sorry. Is this better? Check, Check, Check. Jerry pull the high end out I'm, getting some hiss back here.'"
Brian: Say something about my mother!
Stewie: Oh yes, I'm sorry. I never knew Biscuit as a Dog, but I did know her as a table. She was sturdy, all four legs the same length...
Brian: Thanks. That's enough.
Stewie: Yes. Requiem in Terra Pax, and so forth. Amen

Olivia: You are the weakest link, goodbye.
Stewie: Ha ha ha! Oh gosh that's funny! That's really funny! Do you write your own material? Do you? Because that is so fresh. You are the weakest link goodbye. You know, I've, I've never heard anyone make that joke before. Hmm. You're the first. I've never heard anyone reference, reference that outside the program before. Because that's what she says on the show right? Isn't it? You are the weakest link goodbye. And, and yet you've taken that and used it out of context to insult me in this everyday situation. God what a clever, smart girl you must be, to come up with a joke like that all by yourself. That's so fresh too. Any, any Titanic jokes you want to throw at me too as long as we're hitting these phenomena at the height of their popularity. God you're so funny!

(After Stewie dances, he and Brian are allowed to use a helicopter, which they fly over the mountains)
Stewie:(Over the helicopter's propellers) Brian, be careful cause the mountains are the same color as the sky!
Brian: What?
Stewie: I said be careful cause the mountains are the same color as the- WHOA!!!
Brian: What the hell was that?
Stewie: I'm practicing my comedy crash.
Brian: Well keep it down because I'm trying to-
(The helicopter is about to hit a mountain)
Brian & Stewie: WHOA!!!
(They swerve away from the mountain but the tail of their helicopter hits a cliff, causing them to hit a slope and slide down the mountain, they crash into a rock, sail out of the cockpit and hit the snowbank)
Stewie: Imagine the dance I'm gonna have to do to get our security deposit back.

You know, mother, as first lady of the American stage Helen Hayes once said, "I'm going to kill you"

Brian: (teasing) Stewie loves Lois.
Stewie: Brian loves Olympia Dukakis.
Brian: Oh, yeah I do.

You know mother, life is like a box of chocolates. You never know what you're going to get. Your life, however, is more like a box of active grenades!

(Stewie and Brian begin kissing in order to get thrown out of the Army)
Stewie: Wow, look at how gay we are! I am so gay with my gayness!
Brian: Me, too! I'm...I'm a homo.
Army Guy: Any room for one more?
Stewie: Hell yeah!
(Brian smacks Stewie)

Stewie: Hey, you have a tattoo.
Brian: No I don't.
Stewie: Is that Ziggy? Is that a Ziggy tattoo
Brian: Aw, geez.
Stewie: Why do you have a Ziggy tattoo
Brian: I just to used think he was kind of funny. We should get to the hospital.

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire