Serena, Eric, Lily, they're gonna need us now more than ever. ...
Dan: Serena, Eric, Lily, they're gonna need us now more than ever.
Blair: And not "us." Dan and Blair. Individual entities. Two nouns separated by a conjunction.
Dan: Or a comma, if mentioned in a list.
Blair: Which is rare. Since we have nothing in common and are in fact, opposites.
Dan: The kind of opposites who do not attract.
Blair: Most definitely not.