"You know when you were a little kid and you believed in fairy tales? That fantasy of what your life would be -- white dress, prince charming who’d carry you away to a castle on a hill. You’d lie in your bed at night and close your eyes and you had complete and utter faith. Santa clause, the tooth fairy, prince charming -- they were so close you could taste them. But eventually you grow up and one day you open your eyes and the fairy tale disappears. Most people turn to the things and people they can trust. But the thing is, it’s hard to let go of that fairy tale entirely because almost everyone has that smallest bit of hope and faith that one day they would open their eyes and it would all come true."

MEREDITH

[narrating] "The early bird catches the worm; a stitch in time saves nine. He who hesitates is lost. We can't pretend we haven't been told. We've all heard the proverbs, heard the philosophers, heard our grandparents warning us about wasted time, heard the damn poets urging us to ‘seize the day'. Still sometimes we have to see for ourselves. We have to make our own mistakes. We have to learn our own lessons. We have to sweep today's possibility under tomorrow's rug until we can't anymore, until we finally understand for ourselves like Benjamin Franklin meant. That knowing is better than wondering, that waking is better than sleeping. And that even the biggest failure, even the worst most intractable mistake beats the hell out of never trying."

MEREDITH

PRESTON: "What is this? That we’re doing here. What is it?"
CRISTINA: "You need a definition? You really want to be that guy?"
PRESTON: "Lock the door."

IZZIE: [to Alex] "You are hateful! Hateful! Hateful, arrogant, lazy... hateful man! Hateful!"
DEREK: "Well, never a dull moment here at Seattle Grace. Scalpel?"

MEREDITH: "No. I can't, I'm seeing someone."
ALEX: "Look, if you don't want to go out with me just say so, you don't need to lie."
MEREDITH: "Oh, okay. I don't want to go out with you... and I think I might be seeing someone."

MEREDITH: "Are you really as shallow and callous as you seem?"
ALEX: "Want to grab a drink and hear about my secret pain?"
MEREDITH: "Does that line ever work for you?"
ALEX: "Sometimes."

MEREDITH: "Dr. Shepherd? I'm sorry I called you a jackass."
DEREK: [pauses] "You didn't."
MEREDITH: "Actually I did... twice."

[to patient who threw up on Alex] "You are so my favorite person today."

Izzie

CRISTINA: "If I stab this fork into his thigh, will I get in trouble?"
MEREDITH: "Not if you make it look like an accident."

DEREK: "You know they call you the Nazi."
MIRANDA: "So I've heard."

[to George] "Seriously? You're equating your pathetic love life with my record-breaking tumor? Seriously?"

ANNIE

DEREK: "Miranda."
MIRANDA: "Excuse me?"
DEREK: "Well, that's your name right? It's on your jacket. Fine, I'll just call you Bailey then."
MIRANDA: "You know you think you're charming... in that talented, neurotic, overly moussed hair sort of way. Good for you. But if you think I'm gonna stand back and watch while you favor her-"
DEREK: "I don't favor her. She's good."
MIRANDA: "I'm sure she is."
DEREK: "You know, can I point out, technically, that I'm your boss."
MIRANDA: "You don't scare me. Look, I'm not gonna advertise your extracurricular activates with my intern. However next time I see you favoring Meredith Grey in any way, I'll make sure she doesn't see the inside of an OR. For a month. Just for the sake of balance!"

Grey's Anatomy Season 1 Quotes

"If I miss a real procedure because of this case, they're gonna call me 007, because I killed you."

CRISTINA

ALEX: "Morning, Dr. Model."
IZZIE: "Dr. Evil Spawn."
ALEX: "Ooooh, nice tat. Do they airbrush that out for the catalogs?"
IZZIE: "I don't know. What do they do for the 666 on your skull?"