CRISTINA: "You've never played chess?"
MEREDITH: "I'm not a geek!"

IZZIE: "I have an 11-year old daughter, and she needs a bone marrow transplant. I'm potentially a good match. Please don't tell anyone, please. This isn't a chapter in my history I want everyone to know about."
MIRANDA: "I understand."

IZZIE: [to George] "You don't have to keep avoiding me."
GEORGE: Yeah I do, until this thing blows over, I do. [to people in the clinic] Havier Jugerreo? Havier Jugerreo?

"I came here to be chief. Meredith complicates that."

DEREK

[narrating] "A patient's history is as important as their symptoms. It's what helps us decide if heart burn's a heart attack... if a headache's a tumor. Sometimes patients will try to re-write their own histories. They'll claim they don't smoke, or forget to mention certain drugs... which in surgery can be the kiss of death. We can ignore it all we want, but our history eventually always comes back to haunt us."

MEREDITH

DEREK: "Dr. Colin Marlow."
PRESTON: "The one and only."

DEREK: "Dr. Marlow, Derek Shepherd, neuro. I'm doing a sigal sinus bypass today if you'd like to observe."
COLIN: "Really, that's quite a procedure."
PRESTON: "It's a good trick, but if you're really interested to see what this hospital can do, I'm performing a arterial switch operation for TGA this afternoon."
COLIN: "If you gentlemen are trying to intimidate the competition, it's working."
DEREK: "Good."
COLIN: "I'll see both of you in surgeries."

MEREDITH: "I just agreed to have dinner at my father’s house. Tonight."
DEREK: "Oh."
MEREDITH: "And, Cristina slept with Colin Marlow."
DEREK: "Marlow? Transplant Marlow?"
MEREDITH: "They had a thing when she was a student.
DEREK: "He slept with Christina?"
MEREDITH: "Derek!"
DEREK: "Oh, right, sorry, okay. Um... have dinner at your house. It’s your place, I’ll come. I’ll be your wingman. It’ll be fun. Okay, it won’t be fun. It’ll be fine. They’re your family."
MEREDITH: "Why does everyone assume that?"
DEREK: "Because you deserve to have a family. Even if you don’t like them."

GEORGE: "C'mon! She's Izzie! She's blonde. She's stacked. She's a supermodel. And I'm... I mean, I'm George."
CALLIE: [pauses] "So what does that make me?"

CRISTINA: "Do you remember all the other times I’ve spoken to you about my sex life?"
IZZIE: "No..."
CRISTINA: "Exactly."

IZZIE: "So were there any little blue pills involved, or is he untouched by the miracle of time?"
ALEX: "Dude, that's just wrong, don't answer that."
IZZIE: "C'mon, he's not a young man. He wasn't getting a little help? Popping the pill? Dad's best friend? C'mon, you're going to give me nothing after everything we've been through? Nothing?"
CRISTINA: "It's a miracle drug. And someday it's going to save your life."

IZZIE: "You need to bond with your people. People are what matters."
MEREDITH: "I hate people."

Grey's Anatomy Season 3 Quotes

MEREDITH: "I'm a surgeon. I do the rescuing. You are not my knight in shining whatever."
DEREK: "So we're gonna fight because I pulled you out of the tub."
MEREDITH: "You have a place. You could sleep at it. And then you don't have to pull me out of the bathtub. You're everywhere, all the time, saying things."
DEREK: "This is the happy ever after part. And in the happily ever after, the guy is there all the time, saying things and the girls love it!"
MEREDITH: "Go to work, I'll see you there."
DEREK: "And just for the record? I am your knight in shining whatever."

[in flashback]
Meredith: I have no story. I'm just a girl in a bar.
Derek: I'm just a guy in a bar.