Penny: You look like a talking cupcake!
Pageant Bernadette: And you should pick me for Miss California Quiznos 1999, because I want to...Tell you what I want, what I really really want I'll tell you what I want, what I really really want I wanna, I wanna, I wanna, I wanna Really, really, really be Miss California Quiznos 1999!

You mess with the bull, you get the horns. I'm about to show this guy just how horny I can be.

Sheldon

Leonard: Uh, another one says, "The concept shows some real out-of-the-box thinking".
Sheldon: Do you hear that, Mr. Out-Of-The?
Leonard: I do, indeed, Mr. Box-Thinking.

Leonard: You're sure it's good?
Sheldon: My name is right on there with yours. That is a surefire
mark of quality. That might as well say "Directed by Joss Whedon".
Leonard: Okay, partner, let's do it.

Leonard: You wrote a paper on my idea?
Sheldon: I wrote a paper on our idea.
Leonard: When did my idea become our idea?
Sheldon: When I mixed it with Sheldony goodness and cooked it in the Easy-Bake Oven of my mind.
Leonard: This is good. Our idea is really good.
Sheldon: Well, the light bulb in this oven is ridiculously bright.

Leonard: You're giving me a sticker?
Sheldon: Not just a sticker. That is a sticker of a kitty saying, "Me-wow!"
Leonard: I'm not a preschooler.
Sheldon: Fine, I'll take it back
Leonard: I earned this! Back off!

Leonard: This... is exciting. This is really exciting. I have to go find Sheldon.
Penny: Okay, well, if you find him, use the kitchen island- that coffee table will not support both of you.

Penny: Yeah, I listen to what you say. You're building a particle detector using superfluid helium.
Leonard: You know, when you talk like that, I want to take you right here on this table.
Penny: And you know from past experience this table cannot support both our weight.

Penny: Sheldon, we are just people. we talk about the same things you guys talk about.
Sheldon: You talk about if werewolves can swim?

Sheldon: I don't want to tell you how to do your job, but when a mouse completes a maze it gets a food pellet.
Amy: It also gets its brain plucked out with tweezers.
Sheldon: And its last meal was a food pellet? You're a monster.

I love him, but if he's broken, let's not get a new one.

Penny

Sheldon: Nothing more fun than a paradigm shifting evening of science.
Penny: (to Leonard) And you thought it was soaping me up in the shower.

TBBT Quotes

I just gave you my virginity, woman. Cool your jets!

Sheldon

(Singing) Thor and Dr Jones, Thor and Dr. Jones. One plays with lightening, the other plays with bones.

Howard and Raj