The shocking end of the season in which it is revealed that John Doe is George, and Izzie collapses.
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A terrific scene from the Grey's Anatomy season finale. It wasn't traditional, but this Meredith-Derek "wedding" was very romantic just the same.
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In yet another sneak preview of the Grey's Anatomy finale, Izzie gets some advice on what to do from a patient.
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Alex asks Derek what to do ... not as a doctor, but as a friend.
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In an emotional sneak preview of the Grey's Anatomy season finale, Izzie asks for a vote on what surgical route to take.
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Owen talks to Cristina about his mom. And how he hasn't seen her yet.
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Mark wants Lexie to move in with him in this preview of the season finale ... and sort of gets shot down.
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Hunt and Callie treat a patient you may recognize (Zach Gilford of Friday Night Lights) and his character just wants to get back to Iraq!
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Grey's Anatomy Season 5 Quotes

Minister: Dearly beloved. We are gathered here today to celebrate the wedding of Alexander Michael Karev and Isobel Katherine Stevens. This is a sacred right. An ancient right. As Isobel and Alex prepare to join their lives, it is important to understand that everyone present has played a part in shaping their lives. And, will continue to play a vital role in their continuing future. And thus, we are here not only to witness their vows to each other, but to bestow upon them our blessing. And, now the couple will read their vows.
Izzie: Oh, we didn't write anything.
Alex: No, wait. I have something I wanna say. Today's the day my life begins. All my life I've been just me. Just a smart mouth kid. Today I become a man. Today I become a husband. Today I become accountable to someone other than myself. Today I become accountable to you. To our future. To all the possibilities that a marriage has to offer. Together, no matter what happens, I'll be ready. For anything. For everything. To take on life, to take on love. To take on possibility and responsibility. Today Izzie Stevens, our life together begins. And I for one can't wait.
Izzie: I love you. (kisses him)
Minister: Ahem, not yet!
Alex: Hurry up!
Minister: By the power vested in me, by god and the state of Washington, I now pronounce you husband and wife.
Izzie: Now?
Minister: Now.
(Izzie and Alex kiss)

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)