Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?
Penny: Damn.
Amy: Well, at least, when we do make love, Sheldon won't be thinking about his mother.

Raj: Let's go see if you fit in my man purse.
Bernadette: Heterosexual, my ass.

It's okay, I serve soup to poor people.

Bernadette: Because I'm the one that had it towed.
Amy: You?
Bernadette: Didn't see that one coming, did ya?

Amy: Goodnight, Painting Penny. Goodnight, Real Penny.
Penny: Goodnight, Real Amy.
Amy: You don't have to say goodnight to Painting Amy, because she's never leaving. Bernadette: Goodnight, Real Penny. Goodnight, Transvestite Penny.

Oh, boo-hoo, you're not going to space!

Howard: You know, there's a saying we have at NASA. What makes the right stuff so right is that it always comes home.
Bernadette: Stop talking, Howard.

Penny: He wasn't intellectually stimulating enough.
Bernadette: Couldn't you just fool around with him and then listen to NPR?
Penny: Wouldn't help. Zack couldn't even spell NPR.

Howard's mother had a heart attack because I have sex with him and she can't!

Howard: Two weeks ago I was an astronaut.
Bernadette: Yeah, well, now you're a Smurf. Keep walking.

Uh oh, is someone a little blue?

I'm too small for Twister. And, roller coasters. And sitting with my feet on the floor. Hope you enjoyed the prenatal cigarettes, Mom.

TBBT Quotes

It's very simple. Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and, as it always has, rock crushes scissors

Sheldon

Sheldon: Why do you have the Chinese character for "soup" tattooed on your right buttock?
Penny: It's not "soup," it's "courage."
Sheldon: No it isn't. But I suppose it does take courage to demonstrate that kind of commitment to soup.
Penny: How'd you see it? You said you wouldn't look.
Sheldon: Sorry. As I told you, the hero always peeks.