Blair: That little troll Vanessa's working my last nerve.
Chuck: Not what I expected.
Blair: Until I realized, this could benefit both of us.
Chuck: You had me until "troll."

Chuck: You can't outbid me. How do you expect to win?
Blair: Your lack of focus.

Blair: Serena. What are you doing on campus so early?
Serena: Watching you climb out of a brownstone vestibule with Chuck following like the Bass that ate the canary. And no denials — your skirt's on backwards.

Serena: I know you may find this hard to believe, but not everyone wants to go to Yale because not everyone wants to be Blair Waldorf.
Blair: Not everyone can be.

Blair: How do you know?
Chuck: Because you believe in me.

Blair: My, my. If it isn't Little J, risen from the ashes?
Jenny: I came to tell you in person. You win.
Blair: Oh sweetie, we just started to play.
Jenny: No, you don't understand. I'm done. With you, with them, all of it.
Blair: Just like that, you wave the white flag.
Jenny: I lied. And I stole and I lost the respect for my family. For what, so I can be like you? You asked me before if it was all worth it. And my answer is, it's not.
Blair: I tried to warn you. There's a price to pay. I always knew a girl like you couldn't afford it.
Jenny: Well you were right.

I could care less about his Bassets and probably he's filtering his assets through some foreign government so I won't know.

Serena: It was just so easy in Paris.
Blair: You were just so easy in Paris.

Serena: Whenever something happens that is not part of your plan, you pretend like it doesn't exist. You act like you're in this movie about your perfect life, but I have to remind you that the only one watching it is you. You admitted that your period is late.
Blair: Yes! I've been very stressed. I had that chem test last Friday.

(to Dan) The Ladies Room? I knew you and Serena were having problems, but I had no clue they were anatomical.

Georgina: You're overreacting. The roommate thing is just a coincidence. My parents said it was either Bible camp or college, so ... go Bobcats!
Blair: So you're not in love with Jesus anymore.
Georgina: I still hold Him in my heart, but Jesus and I have redefined our relationship.
Blair: You mean he dumped you because He found out you were Satan!

Blair: Losing my virginity to Chuck Bass? None of my friends will ever understand. I'm ready for my punishment. Whatever you and God think is fair. Flogging, fasting, or putting that thing with the teeth around my thigh like Silas.
Priest: How about some food for thought instead? Don't drink, keep your clothes on, try avoiding those who might cause you to stray.

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.