Chuck: The only reason Waldorf Designs has a future is because I gave mine up for it. My father was right. I always put you first. And you bet against me every time. And now I have nothing.
Blair: You have me.
Chuck: That's not enough. I need a future.
Blair: Then let me be part of it.

Eleanor: That is your third sigh since the seventh arrondissement. Are you having regrets leaving without speaking to Serena?
Blair: Not at all. Those are "I love Paris" sighs.

You've fought for me all year. I've come to fight for you.

Blair: That was your agent. She wants you to reconsider the program in Rome. Which is odd, because you told me they went with someone else.
Dan: Ah, well, yesterday when you ended up with Chuck I was a little nervous about leaving for the whole summer. And I know you told me there were other people there and it was not romantic, but... come on. It's Chuck.
Blair: So you lied to me.
Dan: I figured you would just think I was some jealous freak if I told the truth.
Blair: Well maybe because you are. But you don't have to be. You have nothing to worry about. Take the offer. It's an amazing opportunity and I would never stand in the way of it.
Dan: It means the entire summer apart.
Blair: But it's not like I can't come visit. Rome is just two glasses of chardonnay away.

Blair: Guess what I found out this morning?
Serena: B, I know what you're going to say. But first I really want to tell you—
Blair: Dan turned down the opportunity to spend the summer in Rome with the world's literary luminaries. And do you know why? Because he's scared of leaving me here with Chuck. Can you believe it?
Serena: Sort of.

Blair: I mean the most important thing in a relationship is trust. After sex. And hygiene. And earning potential. Wait. What did you think I was going to say?
Serena: Ah... I mean, it's not important. Nowhere near as important as Dan and Italy and his trust issues. We should get coffee and you should tell me more about it.
Blair: Wait. Okay, using a very generous grading curve and rounding up—because I like your outfit—that lie was a C+ at best. What is going on?
Serena: Something I've been wanting to talk to you about for awhile now. I've been posting on Gossip Girl as Gossip Girl. For a couple of months now.

Serena: When Georgina left town she gave me her laptop and it had a direct link to the Gossip Girl server, passwords, the software, everything.
Blair: S, you had me at Georgina, but I can't believe it. Why didn't you tell me?
Serena: I don't know. I felt like it was something I had to keep secret from everyone. I mean, my best friend even. I know it was wrong and I'm so sorry.
Blair: I mean I could have helped. Sealing fates, forging destinies. Like an imperious Greek goddess. Imposing her will on the guileless masses. But I was wondering why Gossip Girl was being so nice to me lately. And a little off her game. No offense.
Serena: So you're not mad?
Blair: I am furious with you! For not sharing your good fortune and omnipotence. But right now I have to go replace my mother's La Mer before she returns from Paris and discovers I've used it all.

Blair: Chuck, I can't really be seen with you right now. But how are you doing? Are you okay?
Chuck: Far from it. I have to find a way to stop my father from leaving tonight.
Blair: Leaving? But you just found him.
Chuck: He left to keep me safe. Now it's my turn to save him.

Blair: I'm with Chuck.
Serena: B.
Blair: No it's not like that. He needs me. He's going through an extremely difficult time right now.
Serena: Yeah, of course he is. Especially if it means taking you away from Dan to be with him. And you just told me Dan is having trust issues.
Blair: I know, but this is life or death.

Serena: What was Dan's big surprise?
Blair: It was more of an ambush. He got into this writing program in Rome and he wants me to go with him the entire summer.
Serena: How dare he! Blair, that's amazing.
Blair: I told him I had to check my calendar to buy some time to think.
Serena: What's there to think about? Rome for the summer sounds like a dream.
Blair: Not for Romans. The whole place will be crawling with Americans.
Serena: And you can be two of them.
Blair: But it's a big decision. And spending last summer at Louis' side I was hoping to do my own thing.
Serena: So your indecision has nothing to do with Chuck?
Blair: Absolutely not. My concern for him at this time is about something entirely unrelated.
Serena: Which you can't tell me about. B, I hate being out of the loop.

Dan: You don't think this is too much? I mean it's just an interview with one person.
Blair: Well we want to impress him, right?
Dan: I think they're just trying to make sure we're a sane, stable couple. I guess they've had some trouble in the past. Apparently Padma Lakshmi and Salman Rushdie broke up during their stay and it caused all kinds of drama.

Ivy: I'll do whatever it takes to help. I'd love to get back in the gang.
Blair: But just to clarify. In order to be back in the gang, you would have had to be in the gang to begin with.

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.