Blair: What are you doing here, Nate?
Nate: Well, I, um... Look, after rehearsal I just, uh, I couldn't stop thinking about you. I mean, the ball's something we've talked about doing since we were, like, 10. And I've given you every reason to hate me...
Blair: True. Keep going.
Nate: And the Prince, he's a great dancer and all. But, is there any chance you'd go with me instead? For old times' sake?

[to Chuck] Well, I can't be on you, remember? You don't want Nate to find out and I don't want anyone to. You have to learn how to behave yourself first.

Chuck: You looked hot on Prince Theodore's arm, today.
Blair: Is that what I am to you, just an accessory?
Chuck: Next to him, yes. On me, you'd be so much more.

Blair: Carter Baizen is on his way here, right now.
Chuck: What? What the hell are you doing with Carter Baizen?
Blair: He left his jacket here yesterday and I'd rather you be gone when he gets here. There's been enough scenes for today.

Blair: What was that?
Chuck: I should ask you the same question. Perfect gentleman? Perfect date? That broken record was a hit last year. Get with the times, he bores you.
Blair: You almost made a fool of me in front of the New York Times. Which proves my very point; you can't be trusted. Nate is a gentleman; he would never cause a scene.
Chuck: Never get your blood going, either.

Blair: Mom, he's living in Europe... with a man. You can't be all that surprised that he wants a divorce.
Eleanor: I know. But, I am surprised by how it makes me feel. He was my husband, after all. My Harold... for almost 20 years.

Blair: If you think about it, it makes total sense that your mom was a groupie. I mean, only a woman that had completely satisfied her sexual appetite in her youth would ever marry your stepdads.
Serena: Blair, can we not talk about my mom's appetite?
Dan: No, or who satisfied her.
Serena: That's just...
Dan, Jenny, Eric, and Serena: Gross!

Serena: Tell me you didn't sleep with Chuck for revenge?
Blair: Are you jealous?

Blair: Nothing hurts more than sleeping with a best friend.
Serena: Way to prove a point.
Blair: Well I learned it from the master.

Blair: Your mom is freaking out, so my is freaking out.
Serena: Which means you freak out, Blair! Just cut the cord, go nuts! Come on, let's do shots! Come on!
Blair: I told Lily that you were buying a pie.
Serena: Oh, pie.

Blair: I mean, who gets wasted on Thanksgiving?
Serena: The holidays are lonely for people. I wanted to keep them company. Wooooo!

Serena: I thought you wanted to wait. I thought you wanted to make it special.
Blair: Oh, so Nate gets a free pass and I'm the slut?
Serena: Tell me you didn't sleep with Chuck for revenge.
Blair: Well, it wasn't because I liked his natural musk. And, besides, nothing hurts more than sleeping with the best friend. Right, S?

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.