Amy: This year's donations may go to, say, the geology department.
Sheldon: Oh dear, not the dirt people.

Your critical attitude is ruining our Saturday night together, and I'm not above minimizing your window.

It's not a touch phobia, it's a germ phobia. If you'd like to put on a pair of latex gloves I'll let you check me for a hernia.

There once was a brave lad named Leonard, with a fie fie fiddle dee dee. He faced a fearsome giant while Raj just wanted to pee.

I sense that you're trying to slow walk me to an epiphany. Would you mind very much jumping to it.

Penny: Let's try some improvisation.
Sheldon: Why not? It seems you're improvising your entire curriculum.

Sheldon: I didn't want to teach those poopy heads anyway!
Howard: FYI I think that's what Darth Vader said just before he started building the Death Star.

Sheldon: I'm not aware of the acronym KMN.
Leonard: From the context we think it means 'kill me now.'

I was expecting applause but I suppose stunned silence is equally appropriate.

Please tell me you are not having coitus.

Radio contact is sufficient, no need to extend your middle finger.

She made the case that if we break down in the middle of nowhere, your Nebraska backwoods skills and brawny hands will give us the best chance to survive in the wild.

TBBT Quotes

Oh, Bernadette, please play my clarinet.

Raj's poem

Sheldon: I'll have a diet Coke.
Penny: Can you please order a cocktail? I need to practice mixing drinks.
Sheldon: Fine... I'll have a virgin Cuba Libre.
Penny: That's... rum and Coke without the rum.
Sheldon: Yes, and would you make it diet?