Ian: Coming back to the apartment?
Mickey: I like it better on the South Side.
Ian: You're not really giving the West Side a shot.
Mickey: Look, I don't fit in over there, man.
Ian: Neither do I, but, yeah, I'd like to try.
Mickey: I guess that's the difference between you and me.

Frank: I shit myself.
Liam: Ew.

Frank: You always were a beautiful child, Fiona.
Nurse: Thank you.

Oh, we're getting pizza. Fuck yeah.

Mickey

Lip: $75,000, which means $15,000 each.
Ian: You can have mine. We don't need it.
Lip: Thank you, but no thank you.

You remind me of your mother, and that's not a good thing. Good luck.

Debbie

Kev and V. You always stuck your noses in my family's business. You're leaving, so good riddance.

Frank

Fiona: I don’t have the 25k.
Max: You don’t have 25k? Who doesn’t have 25k?
Fiona: Me.

Holy shit, you popped his cherry? And how was the 30 seconds of bliss.

Veronica

I saw how you looked at Steve like a d-o-g in heat.

Veronica

I also danced with Cab Calloway, he had the first colored penis I ever kissed.

Fake Aunt Ginger

Do you know why doctors, lawyers and nurses are great liars? Because they lie to help people.

Steve

Shameless Quotes

Everytime she pees on the stick it's bad news and then I get depressed thinking about my husband banging my mom cause we selfishly wanna have a baby with some of our DNA.

V

Gus: See you at two.
Fiona: Wouldn't miss it.