Hey, you leave my baby alone! She's got nothing to do with this!

Dean

Dean: Hey, maybe we'll have a Snooki sighting.
Sam: What's a Snooki?
Dean: That's a good question.

We've been Parent Trapped.

Dean

I don't like the way Kim Cattrall is looking at me.

Dean

So, what? We've got a bunch of killer dolls? Like Chucky?

Dean

Sam: Wait. That anatomy dummy you were molesting at the lab.
Dean: Excuse me?
Sam: What if that's what this is about?
Dean: What exactly are you accusing me of?

Dean: Be my valentine?
Sam: Dude, we're working. Put it back.
Dean: Have a heart.

Sam: So, Mel Gibson really took a turn this past year, huh?
Dean: Or he's possessed. Seriously. Think about it.

My Spidey senses are tingling.

Dean

[to Sam] My god, son. You're about as cold as they come.

Samuel

Dean: And how would you characterize their relationship?
Girl: Relationship? No, no, they weren't having a relationship.
Dean: Just the tone or the nature of their conversation.
Girl: Well... loud. And athletic?

Dean: So he came by here?
Girl: Oh, he came by a few times.
Dean: Did he? To uh speak to Nicole?
Girl: Right.

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean