Isaac: Scans are now showing much more extensive architecture and a profound increase in the number of lifeforms on the surface.
Kitan: How could that happen in eleven days?
Malloy: Drugs?

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You want to keep your independence but you're frightened of loneliness.

Mercer

You know, these jobs we've chosen? They condition you to be okay being by yourself. And, after a while, you start to think that giving yourself over to someone else is some kind of weakness.

Grayson

Mercer: Cultural contamination of a society that undeveloped is a serious charge. I just don't want to have to come visit you in prison,
Grayson: Really? You wouldn't want to visit a women's prison?

Mercer: Man, if it looks like this going in, I'm afraid of what it looks like coming out.
Clyden: Upsata does not come out. It grows into a parasite within the body. This sensation is intensely pleasurable.

LaMarr: I think we could create a stable quantum bubble inside the shuttle and preserve three-dimensional space.
Dr. Finn: So the outside would be squashed but the inside wouldn't.
Mercer: More space inside than out. Like Doctor Who's phone booth.
Grayson: Or Oscar the Grouch's can.
LaMarr: Or Snoopy's doghouse, yeah.

I want you and I to be okay but you are being a prideful ass.

Grayson

Yaphit: If we match the deflector amplitude to the quantum wave function, it should compensate for any field instability
LaMarr: I like when you talk dirty

Human ambition didn't vanish. The only thing that changed is how we quantify wealth. People still want to be rich. Only now, rich means being the best at what you do.

Grayson

Marcus: Can we help?
Isaac: No, you are small and feeble and you do not possess the necessary intelligence.

Kelly, he fed a guy to another guy. That's not something a department head does.

Mercer

Isaac: Lt. Kitan has exercised Directive 38 in the execution of this program.
Mercer: No bare feet in the Engineering Section?

The Orville Quotes

Mercer: I know Gordon has his issues but we all know that there's nobody that can drive a starship like him.
Admiral: Didn't he once draw a penis on the main viewing screen of Outpost T-85?
Mercer: He's drawn a lot of penises on a lot of things.

Mercer: I've had some personal stuff that's been going on... It's not really worth going into... Can I have one of these mints?
Admiral: Those are marbles.